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In order to obtain more information about liver toxicity, the liver function test was carried out by collecting the serum of the uninfected, the untreated control, MBZ-1 tragacanth and MBZ-OS group. Unlike the results from the histopathological changes, some parameters showed significantly difference between uninfected group and the other groups.
In details, the values I-BIL, AST and ALT of infected mice without treatment were statistically higher than that of uninfected mice. And the orally administration with MBZ did not change the increased I-BIL values but reduced the values of AST and ALT.